The Woody Guthrie Centennial Bibliography

This bibliography updates two extensive works designed to include comprehensively all significant works by and about Woody Guthrie. Richard A. Reuss published A Woody Guthrie Bibliography, 1912–1967 in 1968 and Jeffrey N. Gatten\u27s article “Woody Guthrie: A Bibliographic Update, 1968–1986” appeared in 1988. With this current article, researchers need only utilize these three bibliographies to identify all English-language items of relevance related to, or written by, Guthrie

Crime and Sympathy

Examines the roots of “hard boiled” crime fiction, primarily focusing on Dreiser’s An American Tragedy (1925). Parallels Hemingway with Dreiser through “the way that their ‘anti-sentimentality’ contains a sentimentality which fundamentally informs their projects—and those of their literary descendants.” Looks at Hemingway’s style of anti-sentimental sentimentality in In Our Time, A Farewell to Arms, “The Killers,” and “The Short Happy Life of Francis Macomber.

Man Up, Man Down: The Past and Present of American Toughness

Leonard Cassuto is Professor of English at Fordham University, where he has taught since 1989. He is the author or editor of numerous volumes including The Inhuman Race: The Racial Grotesque in American Literature and Culture, Hard Boiled Sentimentality: The Secret History of American Crime Stories, The Cambridge History of the American Novel, and The Cambridge Companion to Baseball. His latest manuscript, “The Graduate School Mess,” is under contract at Harvard University Press, and he writes a monthly column, “The Graduate Adviser,” for the Chronicle of Higher Education.https://egrove.olemiss.edu/eng_lec/1000/thumbnail.jp

Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice[S]

Elevated hepatic fatty acid elongase-5 (Elovl5) activity lowers blood glucose in fasted chow-fed C57BL/6J mice. As high-fat diets induce hyperglycemia and suppress hepatic Elovl5 activity, we tested the hypothesis that elevated hepatic Elovl5 expression attenuates hyperglycemia in high-fat-diet-induced obese mice. Increasing hepatic Elovl5 activity by a recombinant adenoviral approach restored blood glucose and insulin, HOMA-IR, and glucose tolerance to normal values in obese mice. Elevated Elovl5 activity increased hepatic content of Elovl5 products (20:3,n-6, 22:4,n-6) and suppressed levels of enzymes (Pck1, G6Pc) and transcription factors (FoxO1 and PGC1α, but not CRTC2) involved in gluconeogenesis. Effects of Elovl5 on FoxO1 nuclear abundance correlated with increased phosphorylation of FoxO1, Akt, and the catalytic unit of PP2A, as well as a decline in cellular abundance of TRB3. Such changes are mechanistically linked to the regulation of FoxO1 nuclear abundance and gluconeogenesis. These results show that Elovl5 activity impacts the hepatic abundance and phosphorylation status of multiple proteins involved in gluconeogenesis. Our findings establish a link between fatty acid elongation and hepatic glucose metabolism and suggest a role for regulators of Elovl5 activity in the treatment of diet-induced hyperglycemia